Innovative Production And Separation Methodology For Copper-64 (cu-64)

A new method to optimize and standardize the production and separation of Cu-64, enhancing its availability and uniformity across different sites.

Currently, sites use custom, in-house synthesis modules to produce and separate Cu-64, which leads to a lack of uniformity in Cu-64 products available. Additionally, commercially-available electroplating cells are either expensive, using exotic or costly materials, or insufficient for electroplating of isotopically enriched samples. These complexities have led to a limited number of Cu-64 suppliers, resulting in restricted availability.

This technology introduces a fast, reliable, reproducible, and cost-effective method for the production and separation of Cu-64, utilizing a novel 3-D printed electroplating cell made from readily available materials and standardized separation chemistry integrated into GE FASTlab 2 software. Aimed at overcoming the limitations of current Cu-64 production which relies on custom, in-house synthesis modules, this approach uses widespread and standardized synthesis modules, promising to further standardize procedures, ensuring product uniformity and expanding the isotope's overall availability for medical imaging applications.

• Fast and cost-effective production and separation process.
• Standardization across production sites ensures product uniformity.
• 3-D printable electroplating cell made from readily available materials.
• Integration with widely-used GE FASTlab 2 software for seamless separation.
• Facilitates wider availability of Cu-64 for medical imaging.

Lucia Irazabal
lu.irazabal@utah.edu